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I hope my heart goes first. "Heart Attack (Myocardial Infarction)": Sudden interruption or insufficiency of the supply of blood to the heart, often resulting in death. "Heartbreak": Overwhelming sorrow, grief or disappointment often a result of loss. "Lose (one's) heart to": To fall in love with, often resulting in joy, harmony and bliss. "Heart Failure": Inability of the heart to keep up with the demands on it.